Biosensor Core

Publications

Selected Publications

  1. Kontrogianni-Konstantopoulos A, Jones EM, Van Rossum DB, Bloch RJ (2003) Obscurin is a ligand for small ankyrin 1 in skeletal muscle. Mol Biol Cell 14,1138-1148.
  2. Antolik C, Catino DH, Resneck WG, Bloch RJ (2006) The tetratricopeptide repeat domains of rapsyn bind directly to cytoplasmic sequences of the muscle-specific kinase. Neurosci 141, 87-100.
  3. Lin X, Takahashi K, Liu Y, Derrien A, Zamora PO (2007) A synthetic, bioactive PDGF mimetic with binding to both alpha-PDGF and beta-PDGF receptors. Growth Factors 25, 87-93.
  4. Zhang Y, Hefferin ML, Chen L, Shim EY, Tseng HM, Kwon Y, Sung P, Lee SE, Tomkinson AE (2007) Role of Dnl4-Lif1 in nonhomologous end-joining repair complex assembly and suppression of homologous recombination. Nat Struct Mol Biol 14, 639-646.
  5. Antolik C, Catino DH, O’Neill A, Resneck, WG, Ursitti, JA, Bloch RJ (2007) The actin-binding domain of ACF7 binds directly to the tetratricopeptide repeats of rapsyn. Neurosci 145, 56-65.
  6. Borzok MA, Catino DH, Nicholson JD, Kontrogianni-Konstantopoulos A, Bloch RJ (2007) Mapping the binding site on small ankyrin 1 for obscurin. J Biol Chem 282, 32384-32396.
  7. Bowman AL, Catino DH, Strong JC, Randall WR, Kontrogianni-Konstantopoulos A, Bloch RJ (2008) The rho-guanine nucleotide exchange factor domain of obscurin regulates assembly of titin at the Z-disk through interactions with Ran binding protein 9. Mol Biol Cell 19, 3782-3792
  8. Kwon HJ, Koo JH, Zufall F, Leinders-Zufall T, Margolis FL (2009) Ca extrusion by NCX is compromised in olfactory sensory neurons of OMP mice. PLoS One 4, e4260
  9. Jeong J, Rao AU, Xu J, Ogg SL, Hathout Y, Fenselau C, Mather IH (2009) The PRY/SPRY/B30.2 domain of butyrophilin 1A1 (BTN1A1) binds to xanthine oxidoreductase: implications for the function of BTN1A1 in the mammary gland and other tissues. J Biol Chem 284, 22444-22456.
  10. Ruiz-Perez F, Henderson IR, Leyton DL, Rossiter A, Zhang Y, Nataro JP (2009) Roles of periplasmic chaperone proteins in the biogenesis of serine protease autotransporters of Enterobacteriaceae. J Bacteriol 191, 6571-6583
  11. Zhang Y, Resneck WG, Lee C, Randall WR, Bloch RJ, Ursitti JA (2010) Characterization and expression of a heart-specific alternatively spliced variant of αII-spectrin, cardi+, during development in the rat. J Mol Cell Cardiol 48, 1050-1059.
  12. Weinman EJ, Steplock D, Zhang Y, Biswas R, Bloch RJ, Shenolikar S (2010) Cooperativity between the phosphorylation of Thr95 and Ser77 of NHERF-1 in the hormonal regulation of renal phosphate transport. J Biol Chem 285, 25134-8.
  13. Busby B, Willis CD, Ackermann MA, Kontrogianni-Konstantopoulos A, Bloch RJ (2010) Characterization and comparison of two binding sites on obscurin for small ankyrin 1. Biochem 49, 9948-56.
  14. Zou G, Ochiai H, Huang W, Yang Q, Li C, Wang LX (2011) Chemoenzymatic synthesis and Fcγ receptor binding of homogeneous glycoforms of antibody Fc domain. Presence of a bisecting sugar moiety enhances the affinity of Fc to FcγIIIa receptor. J Am Chem Soc 133, 18975-18991.
  15. Busby B, Oashi T, Willis CD, Ackermann MA, Kontrogianni-Konstantopoulos A, MacKerell AD Jr, Bloch RJ (2011) Electrostatic interactions mediate binding of obscurin to small ankyrin 1: Biochemical and molecular modeling studies. J Mol Biol 408, 321-334
  16.  Willis CD, Oashi T, Busby B, Mackerell AD Jr, Bloch RJ (2012) Hydrophobic residues in small ankyrin 1 participate in binding to obscurin. Mol Membr Biol 29, 36-51.
  17. Jain A, Olsen HS, Vyzasatya R, Burch E, Sakoda Y, Mérigeon EY, Cai L, Lu C, Tan M, Tamada K, Schulze D, Block DS, Strome SE (2012) Fully recombinant IgG2a Fc multimers (stradomers) effectively treat collagen-induced arthritis and prevent idiopathic thrombocytopenic purpura in mice. Arthritis Res Ther 14, R192.
  18. Yang H, Antoine DJ, Andersson U, Tracey KJ (2013) The many faces of HMGB1: molecular structure-functional activity in inflammation, apoptosis, and chemotaxis. J Leukoc Biol 93, 865-873.
  19.  Qiang X, Yang WL, Wu R, Zhou M, Jacob A, Dong W, Kuncewitch M, Ji Y, Yang H, Wang H, Fujita J, Nicastro J, Coppa GF, Tracey KJ, Wang P (2013) Cold-inducible RNA-binding protein (CIRP) triggers inflammatory responses in hemorrhagic shock and sepsis. Nat Med 19, 1489-1495
  20.  Song H, Karashima E, Hamlyn JH, Blaustein MP (2014) Ouabain-digoxin antagonism in rat arteries and neurones. J Physiol 592, 941-969.2.
  21. Schneider CS, Perez JG, Cheng E, Zhang C, Panagiotis M, Hanes J, Winkles JW, Woodworth GF,Kim AJ (2015) Minimizing the non-specific binding of nanoparticles to the brain enables active targeting of Fn14-positive glioblastoma cells. Biomaterials 42, 42-51.
  22. Schneider CS, Bhargav A, Perez JG, Wadajkar A, Winkles JA, Woodworth GF, Kim AJ (2015) Surface plasmon resonance as a high throughput method to evaluate specific and non-specific binding of nano therapeutics. J Contr Release 219, 331-344.
  23. Dancy JG, Wadajkar AS, Schneider CS, Mauban JRH, Woodworth GF, Winkles JA, Kim AJ (2016) Non-specific binding and steric hindrance thresholds for penetration of particulate drug carriers within tumor tissue. J Contr Release 238, 139-148.
  24. Qiang X1, Yang WL, Wu R, Zhou M, Jacob A, Dong W, Kuncewitch M, Ji Y, Yang H, Wang H, Fujita J, Nicastro J, Coppa GF, Tracey KJ, Wang P. Cold-inducible RNA-binding protein (CIRP) triggers inflammatory responses in hemorrhagic shock and sepsis. Nat Med. 2013 Nov;19(11):1489-95.